In the current study, the scientists installed up to five distinct mutations on a single lambda phage genome without counterselection in only a few hours of hands-on time.

Phage therapy may be an effective alternative to antimicrobial drugs in treating bacterial infections. Last month, researchers published the first results from the ELIMINATE clinical trial.

Phage therapy has been around for more than 100 years, but with the advent of antibiotics and a possible influence of an unfavorable review published in the Journal of the American Medical ...

In the lytic cycle, the phage turns the bacterium into a factory for additional phages, until the cell is full of phages and the bacterium bursts and dies. In the lysogenic cycle, the phage ...

Once phages attach to a host, they pursue either a lytic or lysogenic replication strategy. 2 In lytic replication, the phage introduces its viral genome into the cytoplasm and uses the host cell ...

This terminase complex packages DNA into phage heads during assembly of mature phages, which are released by host lysis. In the alternative lysogenic cycle, phage DNA instead integrates into the host ...

The lytic and lysogenic cycles are the two main phases of a virus’ infective lifecycle and route to replication. The lytic cycle, or virulent infection, involves a virus taking control of a host cell ...

To build your first Java AWS Lambda function, just create a simple class with an instance method that performs the following functions: Takes a String as an argument. Returns a String. Writes to the ...

Misson, P., Bruder, E., Cornuault, J. K., et al. (2023) Phage production is blocked in the adherent invasive Escherichia coli LF82 upon macrophage infection.