Adipocytes are cells specialised in storing energy as fat, mainly triglycerides, in organelles called lipid droplets. There are two major types of adipocytes in mammals: white adipocytes contain ...

2.3 HE staining of adipose tissue Fresh adipose tissue was fixed in 4% paraformaldehyde at 4°C for 24 h, washed three times with PBS (10 min per wash), then dehydrated through a graded ethanol series ...

A groundbreaking study reveals that neurons can burn fat, challenging the long-held belief that the brain relies solely on glucose for fuel.

Background Adipose tissue-derived stem cells (ADSCs), a type of mesenchymal stem cells (MSCs), have great potential as therapeutic agents in regenerative medicine. Numerous animal studies have ...

Lipid Droplet: A dynamic organelle that stores neutral lipids and plays roles in energy homeostasis and cellular signalling. Lipolysis: The metabolic process of breaking down lipids to release ...

Multimodal molecular imaging data were collected from 29 donor kidney tissues. Each tissue section was subjected to AF microscopy, MALDI IMS, and PAS-stained microscopy, in sequential order (A).

Relationship between adiposopathy (pathogenic adipose tissue) and metabolic disease. Increased circulating FFAs may be lipotoxic to muscle, liver and pancreas. When adipocytes become excessively ...

Alzheimer's disease (AD) is a detrimental neurodegenerative disease with no effective treatments. Due to cellular heterogeneity, defining the roles of immune cell subsets in AD onset and progression ...

Growing evidence suggests a critical role for overnutrition in the development of low-grade inflammation. Specifically, chronic inflammation in adipose tissue is considered a crucial risk factor for ...

In the lean, healthy state, adipose tissue (AT) has critical roles in maintaining organismal homeostasis. Paramount among the various roles of AT is the regulation of whole body metabolism. While ...

Objective Diverticular disease is a common complex disorder characterised by mucosal outpouchings of the colonic wall that manifests through complications such as diverticulitis, perforation and ...

The study assessed the effects of reduced protein (RPD) vs high protein diet (HPD) in combination with n-3/n-6 PUFA-containing plant oils [linseed oil (LO)/sunflower seed oil (SO)] supplementation on ...