More information: Jennifer H. Hammel et al, Interstitial fluid flow in an engineered human lymph node stroma model modulates T cell egress and stromal change, APL Bioengineering (2025).

The model functions like a lymph node-on-a-chip, recreating aspects of the human lymph node environment - including fluid flow and cellular interactions - to study immune behavior outside the body.

The lymph node stroma model offers a platform to test complex fluid flow and retention of T cells, which support the immune system and fight disease.

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