The different functions of M1 and M2 macrophages are also associated with changes in the metabolic pathways they use to produce ATP. Drs. Galván-Peña and O’Neill discuss the differences in metabolism ...

3.3 CACN136 regulates macrophage polarization and lipid metabolism in vitro 3.3.1 Regulation of LPS-induced macrophage RAW264.7 M1/M2 polarization by CACN136 The effect of CACN136 on the viability of ...

Essential for OXPHOS and FAO metabolism in M2 macrophages is the generation of α‐ketoglutarate from glutamine, the most abundant extracellular amino acid (Liu et al, 2017). α‐ketoglutarate is a ...

The Drumnakilly Road in Omagh is blocked following a road traffic collision near the junction with Camlough Road. Police are asking road users to avoid the area and seek alternative routes.

Road users are advised that a number of parades are expected to take place throughout Belfast on Sunday, 29th June 2025 in the north, south, east and west areas of the city. These will start at ...

COPD is set to become the third leading cause of death globally by 2023. To date, we have no significant disease modifying therapies. COPD patients experience chronic inflammation and defective innate ...

Alveolar macrophage (AM) development and function depends on signature transcription factor peroxisome proliferator-activated receptor-γ (PPARγ). The regulation of PPARγ stability during AM ...