News

ascopubs.org2d
Effect of machine learning-based integration develops M2 macrophage-activation genes signature on outcomes in nasopharyngeal carcinoma. - ASCO Publications
Background: The M2 macrophages are independent prognostic factors in nasopharyngeal carcinoma (NPC). Nevertheless, the clinical significance of M2 macrophages remains largely unexplored. Methods: We ...
Obese mice live 26% longer with a single protein overexpression
University of Texas Southwestern Medical Center scientists found that activating fibroblast growth factor 21 (FGF21) ...
Frontiers20d
Cordycepin, lactoferrin, and Sargassum fusiforme polysaccharides protects against RSV via M2-like macrophage polarization - Frontiers
Results: CLS treatment improved lung pathology, reduced BALF injury markers, and decreased viral load. The therapeutic effects of CLS were abrogated by macrophage depletion, indicating a reliance on ...
PNAS23d
RACK1 promotes the development and function of alveolar macrophages through directly binding to and stabilizing PPARγ - PNAS
Alveolar macrophage (AM) development and function depends on signature transcription factor peroxisome proliferator-activated receptor-γ (PPARγ). The regulation of PPARγ stability during AM ...