Adenosine deaminase 2 (ADA2) plays a critical role in immune regulation, particularly in monocyte differentiation and ...

Macrophages are immune cells with a split personality: some fight tumors, while others help them grow. In breast cancer, most ...

In a surprising twist on cellular metabolism, scientists have uncovered a noncanonical role of the metabolic enzymePHGDH in ...

A silk-based nanocomposite hydrogel delivers dexamethasone + kartogenin to reduce inflammation and regenerate cartilage ...

Tumor associated macrophages (TAMs) are pivotal in the tumor microenvironment, influencing angiogenesis, metastasis, and immunosuppression. This study explores macrophage polarization using a ...

This important study looks into the effect of exogenous CoA on the response of TLR4-activated macrophages. Specifically, CoA enhances the LPS response by examining metabolomics, 13C tracing, and ...

Glucan-mediated trained immunity activates alveolar macrophages which exacerbates acute lung injury induced by LPS.