Adenosine deaminase 2 (ADA2) plays a critical role in immune regulation, particularly in monocyte differentiation and ...

Macrophages are immune cells with a split personality: some fight tumors, while others help them grow. In breast cancer, most ...

In a surprising twist on cellular metabolism, scientists have uncovered a noncanonical role of the metabolic enzymePHGDH in ...

A dual-drug hydrogel using dexamethasone and kartogenin supports cartilage repair by controlling inflammation and promoting ...

Tumor associated macrophages (TAMs) are pivotal in the tumor microenvironment, influencing angiogenesis, metastasis, and immunosuppression. This study explores macrophage polarization using a ...

This important study looks into the effect of exogenous CoA on the response of TLR4-activated macrophages. Specifically, CoA enhances the LPS response by examining metabolomics, 13C tracing, and ...

Patients with ovarian clear cell carcinoma (OCCC) whose tumors have specific mutations in the PPP2R1A gene were found to have ...

Glucan-mediated trained immunity activates alveolar macrophages which exacerbates acute lung injury induced by LPS.