Glucan-mediated trained immunity activates alveolar macrophages which exacerbates acute lung injury induced by LPS.

Macrophages are immune cells with a split personality: some fight tumors, while others help them grow. In breast cancer, most ...

In a surprising twist on cellular metabolism, scientists have uncovered a noncanonical role of the metabolic enzymePHGDH in ...

Adenosine deaminase 2 (ADA2) plays a critical role in immune regulation, particularly in monocyte differentiation and activation. Unlike ADA1, which primarily functions intracellularly, ADA2 can be ...

Meanwhile, M1-type macrophages that were located further away from tumor cells were significantly associated with better disease-free survival (HR, 0.44; P = .017).

According to the new report, the Macrophage Marker Market is estimated to be valued at US$ 256.2 million 2023 to US$ 398.2 million by 2030 at a compounded annual growth rate (CAGR) of 6.5% during the ...

Induction of NF-κB signaling is responsible for gene expression changes leading to M1 macrophage polarization. In sepsis patients, significantly elevated TLR4-TIR acetylation is observed in CD16+ ...

The simultaneous use of both CDg18 and the M1 probe, CDr17, facilitated dual-color monitoring macrophage reprogramming in real-time which was defined by the diminishing M2 character and emergence of ...

M1 and M2 are activated macrophages that protect our immune system and maintain homeostasis. Interestingly, they are characterized by distinct and opposing phenotypes. M1 macrophages are known for ...