Iron-containing macrophages, present in various tissues in patients with iron-storage diseases, have been demonstrated to pass from the intestinal villus into the intestinal lumen, acting to transp ...

We show that melanoma-secreted melanosomes passaged through epidermal keratinocytes or dermal fibroblasts can be further engulfed by resident macrophages. This process leads to macrophage polarization ...

Down-regulation of GAS6 by M1 macrophages resulted in impaired efferocytosis for synovial apoptotic cells, causing synovial hyperplasia and obesity-associated OA development.

To further study the role of monocytes and macrophages in circulating blood as HIV reservoirs, the Johns Hopkins-led team of scientists obtained blood samples between 2018 and 2022 from 10 men ...

A phase 1, first-in-human (FIH) study of adenovirally transduced autologous macrophages engineered to contain an anti-HER2 chimeric antigen receptor (CAR) in participants with HER2 overexpressing ...

Evidence suggests that early clearance of Mtb infection is associated with robust innate immune responses in resident macrophages. In addition to lung-resident macrophage subsets, the recruited ...

They compared the processes in macrophages with a normal cholesterol metabolism with those in macrophages with an altered cholesterol metabolism.

Now, a team of researchers in China and Australia has shown that SARS-CoV-2 infection can affect bone marrow macrophage (BMM)-to-osteoclast differentiation, which may impact the skeletal system.

Does culture media containing the growth factor GM-CSF (granulocyte macrophage colony-stimulating factor) improve the chances of a pregnancy and live-born baby, and reduce the risk of miscarriage, ...

Background and Purpose— Enhancement of erythrophagocytosis by macrophages in a timely manner can limit the toxic effects of erythrocyte metabolites and promote brain recovery after intracerebral ...