Glucan-mediated trained immunity activates alveolar macrophages which exacerbates acute lung injury induced by LPS.

Tumor associated macrophages (TAMs) are pivotal in the tumor microenvironment, influencing angiogenesis, metastasis, and immunosuppression. This study explores macrophage polarization using a ...

This important study looks into the effect of exogenous CoA on the response of TLR4-activated macrophages. Specifically, CoA enhances the LPS response by examining metabolomics, 13C tracing, and ...

Macrophages are immune cells with a split personality: some fight tumors, while others help them grow. In breast cancer, most ...

Anti atherosclerosis effect and mechanism of a novel curcumin analogue CACN136: regulating macrophage M1/M2 polarization and lipid metabolism Qianjiao Zhao 1,2,3 † Yueting Zhong 1,2,3 † Zheng Li 1,2,3 ...

Tumor-associated macrophages (TAMs) polarization and cytokine levels were analyzed by flow cytometry and enzyme linked immunosorbent assay (ELISA). Western blotting and Real-time reverse transcription ...

Furthermore, macrophages harbor robust DNA-sensing activity. 20 Second, it is well established that M1-like macrophages are proinflammatory and antimicrobial; M2-like macrophages (also referred to as ...

PG3M@GaPP promotes macrophage polarization to the anti-inflammatory M2 phenotype, enhancing immune modulation and bacterial uptake. The platform’s positive charge facilitates endosomal escape, ...