Macrophages acquire distinct phenotypes during tissue stress and inflammatory responses, but the mechanisms that regulate the macrophage polarization are poorly defined. Here we show that tuberous ...

Since the emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), understanding the mechanisms underlying ...

Both changes were consistent with polarization to the M2 phenotype, a reduced inflammatory state. Conversely, macrophages from the mice with beta cells that overexpressed iPLA2beta showed ...

Human exposure to toxic particles drives various diseases. Examples include gout, an acute arthritis driven by monosodium ...

Furthermore, the expression of MAFB in macrophages during AKI is regulated by a pro-inflammatory lipid mediator known as PGE2 ...

Furthermore, the expression of MAFB in macrophages during AKI is regulated by a pro-inflammatory lipid mediator known as PGE2, and MAFB regulates ALOX15 expression under the influence of PGE2. These ...

Macrophage-Producing Compound Found to Reduce Inflammation July 1, 2016 The image, inspired by drawbridges of Saint Petersburg, depicts itaconate disrupting the tricarboxylic acid (TCA) cycle flow.

Inflammatory cells (mainly T cells and macrophages) ... Dynamic aspects of macrophage polarization during atherosclerosis progression and regression. Front Immunol 2014;5:579-579. Crossref. PubMed.

“The macrophage will localize wherever the inflammation is in the brain, so you can see the location of the inflammation. The primary objective, though, is to see if there is inflammation; the ...

Unraveling the role of macrophages in regulating inflammatory lipids during acute kidney injury. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2024 / 09 ...