Now, an interdisciplinary team of researchers has demonstrated a way to overcome the challenge: use a new technique—dubbed fragment correlation mass spectrometry—on a mix of parent peptides ...

New mass spectrometry (MS) methods, collectively known as data independent analysis and hyper reaction monitoring, have recently emerged. These methods hold promises to address the shortcomings of ...

The high-throughput nature of proteomics mass spectrometry is enabled by a productive combination of data acquisition protocols and the computational tools used to interpret the resulting spectra. One ...

The team's work, "MolDiscovery: Learning Mass Spectrometry Fragmentation of Small Molecules," was recently published in Nature Communications. The research team included Mohimani; ...

Mass spectrometry (MS) plays a vital role in many aspects of our lives, from diagnosing illness and detecting food contaminants to fighting fraud. In order for a sample to be analyzed by MS, it must ...

Although extremely powerful, the mass spectrometer randomly samples peptides for fragmentation and is biased to pick those with the strongest signal. Thus, it remains a challenge to reproducibly ...

In a comprehensive white paper titled "Abandoning the Quadrupole for Mass Spectrometry Fragmentation Analysis," MOBILion reveals how harnessing the game-changing capabiliti. News.

Mass Spec Terms. α-Cleavage – The homolytic fragmentation is induced by a radical cation located at a hetero atom.Functional groups can be arranged by their ability to induce α-Cleavages. Allyl ...

Long before mass spectrometry became an important tool for cell biology, it was yielding scientific insights in physics and chemistry. Here is a brief history of how the technology has expanded ...

Mass spectrometry is widely applied in forensic science, ... This has been the gold standard for many years because so many substances fragment to give a clear fingerprint once in the gas phase.

All-ion Fragmentation . All-ion fragmentation (AIF) was first introduced in bench-top Exactive class Orbitrap mass spectrometer that was initially developed for small molecule applications.