Trapped immune cells laden with microplastics starve the brain of oxygen—mouse study links vascular blockages to memory loss and motor deficits, with lingering risks even after symptoms fade.

Cerebral palsy-like brain damage prevented in mice Date: November 4, 2011 Source: Washington University School of Medicine Summary: Scientists have shown that a protein may help prevent the kind ...

Reduced blood flow These laser speckle contrast images show blood flow in the mouse brain at various times after microplastics injection. The images indicate that blockages of microplastic-labelled ...

The change in blood flow that occurred with these slow waves was up to 20% of the entire brain blood supply. Surprisingly, this phenomenon was only weakly tied to changes in brain activity.

Microplastics sit on a human finger with an inset image of blood vessels in the brain. Svetlozar Hristov / mr.suphachai praserdumrongchai/iStock / Getty Images Plus ...

Study Reveals Expanding and Contracting Blood Vessels in Awake Mouse Brain NIH-funded study challenges conventional wisdom about brain blood flow. News ... Broggini T, Duckworth J, Ji X, et al.

For the first time, however, experts succeeded in visually tracking the movement of microplastics through brain blood vessels in mice—and the pile-ups resembled a microscopic “car crash.” ...

To test this, Kitazume and colleagues generated mice that expressed human APP770 specifically in their endothelial cells. These EC-APP770+ mice pumped out high levels of serum sAPP770. At two years of ...

However, the limiting problem in brain gene therapy is delivery to the brain followed by regulation of the expression of the transgene. Present day gene vectors do not cross the blood-brain barrier.

Blood flow makes waves across the surface of the mouse brain Date: May 29, 2024 Source: NIH/National Institute of Neurological Disorders and Stroke ...