Ménière disease is a balance disorder. It’s caused by an abnormality in part the inner ear called the labyrinth. Fluid build-up here can cause a severe spinning sensation (vertigo) and affect the ...

We present the first total synthesis of eight ent-pimaranes via a short and enantioselective route (11–16 steps). Key features of the divergent synthesis are a Sharpless asymmetric dihydroxylation, a ...