New research from UC Davis Comprehensive Cancer Center has uncovered an evolutionary change that may explain why certain ...

Wild tomatoes on the Galápagos Islands may be providing scientists with an unprecedented look at “devolution” according to a ...

In 1977, the Nobel Prize in Physiology or Medicine was awarded to Roger Guillemin and Andrew Schally for their discovery and synthesis of ...

Mutations in EGLN1, the gene encoding for hypoxia-inducible factor (HIF) prolyl-4-hydroxylase 2 (PHD2), cause erythrocytosis and in rare cases the development of neuroendocrine tumors. In the presence ...

Alignment and sequencing errors are a major concern in molecular evolution, and this valuable study represents a welcome improvement for genome-wide scans of positive selection. This new method seems ...

Google's DeepMind launches AlphaGenome, an artificial intelligence model that predicts gene expression from DNA sequence.

In 1977, the Nobel Prize in Physiology or Medicine was awarded to Roger Guillemin and Andrew Schally for their discovery and synthesis of gonadotropin-releasing hormone (GnRH), a key regulator of ...

A new study uncovers the long-elusive mechanism of inhalational anesthetics by identifying the RyR1 calcium channel as a key molecular target.

Researchers in China have developed a machine learning tool that can predict both the stereoselectivity and activity of engineered enzymes by analysing their amino acid sequence. They claim their tool ...

Missense mutations are genetic alterations arising from the substitution of a single base pair (bp) in an amino acid (aa) sequence with a different base pair, resulting in the translation of a ...

In this paper, we find the correlated mutations of positions among structural proteins of spike, envelop, membrane and nucleocapsid proteins in amino acid sequences of SARS-CoV-2. Here, we adopt the ...

What is a missense mutation? A missense mutation occurs when there is a mistake in the DNA code and one of the DNA base pairs is changed, for example, A is swapped for C. This single change means that ...