Mitochondria are organelles – compartments contained inside cells – that serve several functions, ... To study how the movement of mitochondria is related to motor neuron disease, Nguyen developed two ...

H uman brains grow extraordinarily slowly—a trait many neuroscientists speculate is related to our distinctive intellect. But how and why a human neuron takes years to grow when a mouse neuron grows ...

Elizabeth Jonas first got interested in mitochondria by chance. In 1995, she was a postdoctoral researcher at Yale, working ...

Instead, their structure and function vary depending on their location within the neuron. Mitochondria in the farthest reaches of the dendrites of neurons—at the outermost synaptic input ...

The mitochondria from the Miro1-negative neurons behaved normally in several assays. In primary cortical neuron cultures, the mitochondrial membrane potential was normal. Nguyen also isolated ...

Mitochondrial signals alter the expression of more than 66 percent of genes in the ... Glucose has to traverse a number of hurdles before getting to neuron mitochondria—it detours through ...

They mapped the mitochondrial structure in CA2 neuron dendrites of both control and MCU-depleted mice at high spatial resolution with extreme precision over millimeter expanses of tissue. The analysis ...

The neuron is the basic working unit of the brain, and recent studies are beginning to reveal how neurons perform the complex computations that underlie our behavior. The latest study by the ...

A new mouse study from Massachusetts General Hospital has for the first time established a connection between elevated levels of calcium in mitochondria and neuron death associated with Alzheimer ...