The disruption of axons—the thread-like part of nerve cells that transmits electrical signals—is associated with Alzheimer’s disease. One way axonal function may be hindered is through damage to the ...

Lymph node stroma model development. We sought to develop a model of immune cell egress from the lymph node. Credit: APL Bioengineering (2025). DOI: 10.1063/5.0247363 ...

The model functions like a lymph node-on-a-chip, recreating aspects of the human lymph node environment - including fluid flow and cellular interactions - to study immune behavior outside the body.

From Miller Moss to Louisville football's defensive additions, here's what we learned about Jeff Brohm's Cards during the UofL football spring game.

Electrical signal transmission in conductive channels would entail the phenomenon of electromagnetic wave propagation. In nerve fibers, however, the established Hodgkin-Huxley model treats the ...

AbbVie has agreed to pay $65 million on an option deal with start-up Gilgamesh Pharma, lining up rights to neuroplastogen compounds that can improve neuroplasticity - the ability of the brain to ...

There are many target methods that are efficient to tackle the robustness and immunization problem, in particular, to identify the most influential nodes in a certain complex network. Unfortunately, ...

Methods: We analyzed DLBCL patients with secondary CNS involvement who received salvage therapies with curative intent and who underwent high-dose chemotherapy followed by ASCT. We analyzed the ...

Quiver is also scaling their human-centric AI-driven novel CNS drug discovery platform with in silico models of target, efficacy and toxicity prediction, and is further bolstering a pipeline of ...

A node of Ranvier: a single teased sciatic nerve fibre stained for neurofilament (red) and neurofascin (green). Neurofascin is present at the node (centre) and at the paranodal axoglial junctions that ...

After being diagnosed with endometrial cancer, doctors will try to figure out if it has spread and, if so, how far. This process is called staging. The stage of a cancer describes how much and where ...

These custom nodes provide support for model files stored in the GGUF format popularized by llama.cpp. While quantization wasn't feasible for regular UNET models (conv2d), transformer/DiT models such ...