Cancer-fighting T-cells, the immune system's primary enforcers, are scarce in the rare kidney cancer called chromophobe renal ...

Fat isn’t just a guilty pleasure — it’s cancer’s secret weapon. New research from UT Southwestern Medical Center is shedding light on why this is the case.In a study published this month in the ...

The proper frequency of these blood tests depends on your age and personal health status -- the most important thing is to ...

New research by Sumeda Nandadasa, Ph.D., reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, ...

LOS ANGELES — Living-related conjunctival limbal allograft should be first-line therapy for limbal stem cell deficiency, Edward J. Holland, MD, said during Cornea Day at the American Society of ...

INVESTIGATORS AND CLINICIANS anticipate that the next wave of therapeutic approaches in renal cell carcinoma (RCC) will target hypoxia-inducible factor-2 (HIF-2), a transcription factor that is ...

The oncogenic mechanisms by which TFE3 fusion proteins drive translocation renal cell carcinoma (tRCC) are poorly characterized. Here, we integrated loss and gain of function experiments with ...

Meeting Coverage > IKCS CAR T-Cell Therapy for Kidney Cancer Builds on Efficacy Record — Confirmed responses in one-fourth to one-third of patients with refractory disease by Charles Bankhead ...

NKT2152, a novel oral HIF2α inhibitor, demonstrated promising objective response rates (ORRs) for patients with previously treated advanced clear cell renal cell carcinoma (RCC), in both the all-comer ...

Collecting duct carcinoma (CDC) is an aggressive rare subtype of kidney cancer with unmet clinical needs. Little is known about its underlying molecular alterations and etiology, primarily due to its ...

Material and Methods: To examine the effect of MCPIP1 in normal epithelial cell lines TCMK-1, RPTEC-Tert1 and HK-2 were transduced to overexpress mutated, inactive form of MCPIP1 (pLIX D141N) with ...