An efficient method for highly α-regioselective nucleophilic substitution of the Baylis−Hillman acetates with indoles catalyzed by AgOTf in high yields (72−99%) has been developed. Reductive ...

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Electrophilic aromatic substitution (EAS) represents one of the most important classes of reactions in all of chemistry. One of the “iron laws” of EAS is that an electron-rich aromatic ring will react ...