Macrophages are immune cells with a split personality: some fight tumors, while others help them grow. In breast cancer, most ...

This important study looks into the effect of exogenous CoA on the response of TLR4-activated macrophages. Specifically, CoA enhances the LPS response by examining metabolomics, 13C tracing, and ...

In a surprising twist on cellular metabolism, scientists have uncovered a noncanonical role of the metabolic enzymePHGDH in ...

Glucan-mediated trained immunity activates alveolar macrophages which exacerbates acute lung injury induced by LPS.

Inflammation plays a pivotal dual role in disease pathogenesis, acting as both a protective response and a critical factor to chronic inflammatory pathologies. Traditional anti-inflammatory therapies ...