Glucan-mediated trained immunity activates alveolar macrophages which exacerbates acute lung injury induced by LPS.

This important study looks into the effect of exogenous CoA on the response of TLR4-activated macrophages. Specifically, CoA enhances the LPS response by examining metabolomics, 13C tracing, and ...

Macrophages are immune cells with a split personality: some fight tumors, while others help them grow. In breast cancer, most ...

In a surprising twist on cellular metabolism, scientists have uncovered a noncanonical role of the metabolic enzymePHGDH in ...

More information: Rachael Stewart et al, X-Ray Polarization of the Magnetar 1E 1841−045, The Astrophysical Journal Letters (2025). DOI: 10.3847/2041-8213/adbffa ...

It’s not just in policy or party leadership where you see the shift. In 2022, fewer than 30 percent of Republican men believed the proposition that “women should return to their traditional ...

Background: The immune microenvironment of breast cancer is richly infiltrated with macrophages, yet modulation targeting macrophage polarization has failed to achieve significant clinical efficacy.

Background: C/EBPβ is a master regulator of the mesenchymal phenotype in GBM and has an essential role in the maintenance of immunosuppressive M2 tumor-associated macrophages (TAMs). Lucicebtide is a ...

Amid polarization, AI disruption, and eroding trust in institutions, retired four-star General Stanley McChrystal argues that what leaders need now more than ever is character. Head of the ...

More information: Buddhika Nettasinghe et al, How out-group animosity can shape partisan divisions: A model of affective polarization, PNAS Nexus (2025). DOI: 10.1093/pnasnexus/pgaf082 ...

Patients with PBC often experience symptoms such as fatigue and pruritus, which can affect quality of life. “We still do not have any clear evidence of any therapeutic agent improving fatigue ...

News Release 9-Apr-2025 Machine learning approach to investigating macrophage polarization on various titanium surface characteristics Peer-Reviewed Publication BMEF (BME Frontiers) image: ...