BOSTON& EL MONTE, Calif.---- Foundation Medicine, Inc., a genomics company committed to transforming cancer care, today announced plans to launch two new germline tests, FoundationOne ® Germline ...

Foundation Medicine to launch two new hereditary germline tests in the United States through a partnership with Fulgent Genetics.

While adherence to germline testing has been found to be low, one expert explained why tests findings could matter to patients.

Researchers say findings unearth a new class of biomarkers to forecast tumor progression, and a new way of understanding breast cancer origins.

The study revealed unexpected and sex-specific effects of germline regulation on longevity and somatic repair in vertebrates. Contrary to classical evolutionary theories, it turns out that ...

Researchers at Baylor College of Medicine’s Dan L Duncan Comprehensive Cancer Center and Human Genome Sequencing Center investigated the extent to which forms of genetic variation called germline or ...

Study: Germline-encoded specificities and the predictability of the B cell response. Image Credit: Kateryna Kon/Shutterstock.com Background Although the evolution of the immunoglobulin genes that ...

In the graphic, I use a germline BRCA2 mutation as an example. But there are actually over 50 known hereditary cancer syndromes caused by different germline mutations, according to the National Cancer ...

A Phase 1 clinical trial provides promising results for a broadly neutralizing antibody (bnAb) HIV vaccine, according to a new study. The findings of this first-in-humans test establish a clinical ...

In an analysis of cancer-causing pathogenic germline variants (PGVs) among 7788 patients with lung cancer, almost all PGVs identified among these patients were found to be potentially clinically ...

Molecular tumor profiling is becoming a routine part of clinical cancer care, typically involving tumor-only panel testing without matched germline. We hypothesized that integrated germline sequencing ...

The role of Ire1 in muscle regeneration was tested in mice with a germline conditional deletion of Ire1 under a muscle creatine kinase promotor. The conditional Ire1 knockout diminished myofiber size ...