Using 2-DOG uptake assays, we found that two independent podocyte cell lines were each capable of increasing their glucose uptake by 90 and 105%, respectively, after 15 min of stimulation with 220 ...

Primary human cell derived (excluding murine podocyte cell line) Physiologically relevant phenotype analogous to in vivo differentiated renal cells. Homogenous, stable and long-lasting; ...

A New Era of Podocyte-Targeted Therapy for Proteinuric Kidney Disease Author : Börje Haraldsson , M.D., Ph.D. Author Info & Affiliations Published December 19, 2013 ...

Podocytes are a terminally differentiated cell type located in the glomerulus. Podocyte damage and the subsequent dysregulation of podocyte proteins have been implicated in various kidney disorders.

PEMP analysis confirmed that ELX-02 treatment improved podocyte foot process effacement in all three patients with an average post-treatment increase in FSD of 60% as compared to baseline levels.

Cell/Tissue Culture. Cell lines, Cell growth, Cell differentiation Chemicals and Reagents. Reagent kits, Laboratory chemicals Drug Discovery and ... as Alport syndrome (AS). To study the cellular and ...

SAN DIEGO, June 11, 2025--(BUSINESS WIRE)--Travere Therapeutics, Inc., (Nasdaq: TVTX) today announced that the Company will present three abstracts on the effect of FILSPARI (sparsentan) in rare ...

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 14, entitled, "Inhibiting NLRP3 signaling in aging ...

Discussion. In this study, we have demonstrated, using two independent normal podocyte cell lines, a previously unsuspected aspect of human podocyte biology: that differentiated podocytes are ...