A research team has identified the signaling mechanisms underlying podocyte formation, or morphogenesis. The discovery opens the door to the development of therapies to stimulate the regeneration of ...

Discussion. In this study, we have demonstrated, using two independent normal podocyte cell lines, a previously unsuspected aspect of human podocyte biology: that differentiated podocytes are ...

Cycles of controlled fasting may promote regeneration of podocytes in patients with primary glomerulonephritis, a pilot study suggests. After conducting various animal studies, Laura Perin, PhD ...

SAN DIEGO, June 11, 2025--Travere Therapeutics today announced that the Company will present three abstracts at the upcoming International Podocyte Conference.

Podocytes are a terminally differentiated cell type located in the glomerulus. Podocyte damage and the subsequent dysregulation of podocyte proteins have been implicated in various kidney disorders.

A team led by Iain Drummond, Ph.D., of the MDI Biological Laboratory in Bar Harbor, Maine, has identified the signaling mechanisms underlying the formation of podocytes, which are tiny, highly ...

From: “MicroRNAs in Podocyte Injury in Diabetic Nephropathy” Ishii et al. 2020 ... The damage can be so severe in some cases that it disrupts the regeneration of new podocytes.

In recent years, the MDI Biological Laboratory has become a hub for kidney regeneration research due to its participation in a National Institutes of Health (NIH)-funded consortium, (Re)Building a ...

Using 2-DOG uptake assays, we found that two independent podocyte cell lines were each capable of increasing their glucose uptake by 90 and 105%, respectively, after 15 min of stimulation with 220 ...