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Nature Reviews Nephrology - Albuminuria inhibits podocyte regenerationPrevious studies by Romagnani and colleagues, and by other groups, have shown that RPCs in the Bowman capsule can ...
A research team has identified the signaling mechanisms underlying podocyte formation, or morphogenesis. The discovery opens the door to the development of therapies to stimulate the regeneration of ...
In this study, we have demonstrated, using two independent normal podocyte cell lines, a previously unsuspected aspect of human podocyte biology: that differentiated podocytes are insulin ...
Controlled fasting in adults with primary glomerular kidney disease may help protect the organ, preliminary research suggests.
SAN DIEGO, June 11, 2025--Travere Therapeutics today announced that the Company will present three abstracts at the upcoming International Podocyte Conference.
Podocytes are a terminally differentiated cell type located in the glomerulus. Podocyte damage and the subsequent dysregulation of podocyte proteins have been implicated in various kidney disorders.
As a result of the limited options, kidney research at the MDI Biological Laboratory has focused on the regeneration of kidney tissue, and especially of nephrons, the functional units of the ...
Now that the kidneys, and particularly podocyte cells, have been identified as vulnerable targets for Covid-19, there is a critical need to develop novel vaccines and antiviral treatments that ...
The discovery of the signaling mechanism underlying podocyte formation will play a critical role in generating replacement kidney tissue.
C: GLUT1 immunogold localization in normal human glomerular sections. a: Section through the filtration barrier. GLUT1 is found at the podocyte cell surface and in intracytoplasmic vesicles (v).