A team at the Peter Mac is planning for first-in-human trials in five years, hoping this new therapy will eschew the ...

Cis-regulatory elements (CREs)—including promoters, enhancers, silencers, and insulators—are critical non-coding DNA ...

The FDA’s Orphan Drug Designation offers incentives like seven years of U.S. market exclusivity, tax credits for clinical ...

This study demonstrates that Setd2 overexpression rescues bivalent gene expression during zygotic genome activation (ZGA) in ...

Editas Medicine, Inc. (NASDAQ:EDIT) ranks among the best CRISPR stocks to buy. At the European Hematology Association 2025 ...

Actinomycetes are important organisms for the biosynthesis of valuable natural products. However, only a limited number of well-characterized native constitutive promoters from actinomycetes are ...

a, Co-transfection of an ARF promoter-driven reporter plasmid containing two Gal4-binding sites with Gal4-Rb or Gal4-DNMT1 into HCT116 cells results is repression of reporter gene activity.

More than three decades after the rape of a 12-year-old girl, investigators say DNA evidence allegedly links a Brockton man to the assault.

A deep-learning model trained on human data reveals that promoter mutations may explain a significant portion of unsolved ...

The first gene therapy clinical trials were initiated more than two decades ago. In the early days, gene therapy shared the fate of many experimental medicine approaches and was impeded by the ...