In the hippocampus, a critical brain region for learning and memory, new cells emerge in some people into late adulthood, ...

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Two weeks after agreeing to be bought out by Sanofi, Vigil Neuroscience’s monoclonal antibody iluzanebart failed a Phase II study for a rare brain disorder and its development is being discontinued.

They targeted two primary cell types: pyramidal tract (PT) neurons and intratelencephalic (IT) neurons. When PT neurons were silenced, psilocybin lost its therapeutic power—while silencing IT neurons ...

Now, Cornell University researchers have identified a pair of key neurological mechanisms in the brain – a cell type and receptor – that enable the psychedelic compound's long-lasting effects.

Summary: Researchers have uncovered two key brain mechanisms—specific neurons and a serotonin receptor—that help explain how psilocybin produces long-lasting antidepressant effects. Their study ...

These neurons are found in the outer layers of the brain and are particularly important in processing and relaying information. A recent study conducted by researchers from VIB-KU Leuven and the ...

7 January 2025, Leuven – Specific brain cells known as layer 5 pyramidal neurons play a vital role in how our brains process information. Research by the team of Prof. Joris de Wit (VIB-KU ...

Research by the team of Prof. Joris de Wit (VIB-KU Leuven) and colleagues highlights the differences between two types of these brain cells —intratelencephalic (IT) neurons and pyramidal tract ...

To understand how these brain cells exchange information through their synapses (junctions to exchange chemical ‘messages’), the team of Prof. Joris de Wit (VIB-KU Leuven Center for Brain and Disease ...

Objective: To study the pyramidal tract side effects (PTSEs) induced by the spread of current from the subthalamic nucleus (STN) to the pyramidal tract (PT), in patients with parkinsonism undergoing ...