Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

The structure and chemistry of nucleic acids is fundamental to their function, from the DNA double helix discovered by Watson and Crick to the intricate secondary and tertiary structures adopted by ...

Xeno nucleic acids are essential for the development of nucleic acid-based drugs. To be effective, they need to be able to stably bind to natural RNA (a cellular single-stranded version of the DNA ...

Researchers need to consider targeting exotic, noncanonical nucleic acids—that is, alternative and multistranded DNA and RNA structures. Local transitions in the structure of canonical ds-B-DNA ...

A new gene therapy delivery device could let hospital pharmacies make personalized nanomedicines to order. This democratized ...

Other forms of both DNA and RNA exist that subvert the classical structures of these nucleic acids. Z-DNA While the structure of DNA you will see above – and in any biology textbook you might care to ...

Much of the research at Rockefeller has revolved around the nucleic acids RNA (ribonucleic acid) and DNA (deoxyribonucleic acid) and proteins. Chemistry of Nucleic Acids (DNA and RNA) When Oswald T.

Get Instant Summarized Text (Gist) A bacterial pathogen enhances gut colonization by regulating N-acetylneuraminic acid (Neu5Ac) metabolism through a novel small noncoding RNA.

Christiansen, M. E. and Znosko, B. M. (2009) Thermodynamic characterization of tandem mismatches in naturally occurring RNA, Nucleic Acids Res. 37, 4696-4706. 12 Davis, A. R. and Znosko, B. M. (2008) ...

Co-polymerization of glycol nucleic acid monomers with dicarboxylic acids in simulated early Earth drying environments readily gives rise to plausible prebiotic xeno nucleic acid co-polymers ...