Regulatory T cells represent a distinct T-cell subset that has a key role in inducing and maintaining immunological tolerance. Several different regulatory T-cell subsets have been described.

Researchers at Tsukuba University have discovered that the increase in regulatory T (Treg) cells, which typically suppress ...

Scientists have long known that Foxp3 is key to regulatory T cell development, but only as an on-off switch for regulatory T cell genes. Zheng believed this view of Foxp3 as a simple genetic ...

New research has identified the gene Egr-1 as a critical regulator of immune balance, offering hope for autoimmune disease therapies.

Liston is a senior author of the team’s published paper in Immunity, titled “The tissue-resident regulatory T cell pool is shaped by transient multi-tissue migration and a conserved residency ...

Children's Hospital of Philadelphia. (2023, April 7). Two different regulatory T cell populations. ScienceDaily. Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2023 / 04 ...

Celiac disease is also a good candidate for regulatory T-cell therapy because in more than 90% of patients it is caused by a genetic variant called HLA-DQ2.5, Muller added.

Immunologists from the Institute have been the first to uncover a role for a family of RNA binding proteins in the function of regulatory T cells in the immune system. As their name suggests ...

How regulatory T cells halt aberrant, self-reactive T cells Study reveals new therapeutic target to subdue autoimmune inflammation caused by loss of regulatory T cell function ...