The actin cytoskeleton is a dynamic network made up of actin polymers and associated actin binding proteins. The actin cytoskeleton was originally isolated as a component of the actomyosin complex ...

The cytoskeleton of a cell is made up of microtubules, actin filaments, and intermediate filaments. These structures give the cell its shape and help organize the cell's parts.

Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity. Cancer Research , 2018; 78 (19): 5631 DOI: 10.1158/0008-5472.CAN-18-0441 Cite This Page : ...

SETD2, known for its involvement on gene expression, also can affect functions controlled by the cytoskeleton, such as movement, metastasis and migration, which are very important for cancer cells.

The actin cytoskeleton is essential for maintaining the shape of cells and enabling motility, and plays critical roles in tumor cell invasion and metastasis.

This actin shell selectively and subtly unwraps the ER from mitochondria and delays the initial phases of the Pink/Parkin dependent mitophagy pathway. To achieve the mechanistic information on actin’s ...

Not only have researchers identified how a common cellular protein affects aging, but they’ve tweaked the genes that produce it in fruit flies, extending healthy lifespan by 25% to 30%. The ...

An interdisciplinary team lead by Peter Bieling and Stefan Raunser from the Max Planck Institute of Molecular Physiology in Dortmund has now revealed a previously unknown mechanism, explaining how ...

Study identifies key protein that helps regulate the actin cytoskeleton. A recent study led by Assistant Professor of Gerontology Ryo Sanabria has identified a key protein that helps regulate the ...

The actin cytoskeleton provides force for dynamic cellular processes, such as motility, morphogenesis, cell division, endocytosis, and phagocytosis. The organization and dynamics of actin filaments ...

More information: Antoun Al Absi et al, Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity, Cancer Research (2018). DOI: 10.1158/0008-5472 ...