FDA warns of severe itching risk when stopping long-term use of allergy medications cetirizine and levocetirizine, affecting quality of life for some users.

However, the underlying conditions necessitating amputation, such as severe infections (e.g., sepsis), extensive gangrene, or thrombotic (blood clotting) disorders, can significantly increase ...

Caliente, whose real name was Bianca Castro, passed away on Sunday (April 27), just days after undergoing a leg amputation following a severe infection. Her family announced the sad news in a post ...

Activation and targetability of TYMP–IL-6–TF signaling in the skin microenvironment in uremic calciphylaxis. Science Translational Medicine, 2025; 17 (795) DOI: 10.1126/scitranslmed.adn5772 ...

One of them, calciphylaxis, typically affects patients with end-stage, advanced kidney disease. It is a condition characterized by severe, painful and non-healing skin ulcers with no known cure.

Among the most severe outcomes is the risk of foot or leg amputation, a reality that many people with diabetes must actively work to prevent.

5 reasons diabetics face higher amputation risks Understanding and preventing severe diabetes complications By Health IQ digital Nov 08, 2024 7:00 am Photo credit: Shutterstock.com / LightField ...

In severe cases of tissue death, there’s a possibility of amputation. This is commonly performed on arms, legs, fingers, or toes. Calciphylaxis isn’t curable, but remission is possible.

Lexi Reed shows off the spot on her arm where she would receive infusions for calciphylaxis. Lexi Reed/Instagram Reed, 33, was diagnosed with the condition after suffering from severe kidney ...