Tucked away in the embrace of the Shawnee National Forest sits Makanda, Illinois – a pocket-sized paradise that might be the Midwest’s best-kept secret.

Whether you call it St. Louis, the Gateway to the West, the 314 or simply “The Lou,” St. Louis has a way of offering ...

St. Louis, Detroit, and Pittsburgh are the last affordable markets for median-income buyers to purchase a home, with the ...

The former CEO of St. Louis Development Corp. signed a severance agreement with the agency.

ST. LOUIS COUNTY — Three longtime north St. Louis County politicians are poised to run in next year’s Democratic primary to represent the 1st District on the County Council, according to ...

A St. Louis woman was sentenced to 13 years in prison Monday after pleading guilty to killing the father of her child.

ST. LOUIS — Saint Louis University is enrolling 70 volunteers to study a new vaccine for yellow fever. A new vaccine is needed because the current vaccine is unsafe for those with egg allergies and an ...

With the County in charge of administering some federal programs, changes to funding will impact their work.

A pair of first cousins are primed to wreak havoc on opposing NFL defenses in 2025.

Map of St. Louis area, showing travelers where the best hotels and attractions are located.

Detroit and Grand Rapids aren't the most exciting places to live, FinanceBuzz says, but they won't put you to sleep like ...

Watch live news from St. Louis on 5 On Your Side. Stay up to date on what's happening in your community with a 24/7 live stream and on demand content from 5 On Your Side 5+ features the latest ...