In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be ...

GREmLN leverages a graph-based architecture to represent gene-gene interactions to predict cell behavior for therapeutic ...

A research team at KAIST has identified the core gene expression networks regulated by key proteins ... The team discovered that IPMK binds directly to SRF, altering the three-dimensional structure of ...

Nanoscope Therapeutics is on the brink of filing what could be the first mutation-agnostic gene therapy for incurable eye disease retinitis pigmentosa.

3D Structure Key to Shaping Gene Activity Sanford Burnham Prebys In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension.

Signals for Gi alpha-2 and the stimulatory G protein alpha-subunit Gs alpha were specific and due to hybridization of nascent mRNA transcripts. In the isoprenaline group the transcriptional activity ...

Artificial Gene Regulation by RNA Molecules It is increasingly clear that small RNA molecules play roles in natural gene regulation. Can new examples be engineered? The Nucleic Acid Structure and ...

Objective Both the gut microbiome and host genetics are known to play significant roles in the pathogenesis of IBD. However, the interaction between these two factors and its implications in the ...

Haploinsufficiency of the human homeobox gene ALX4 causes skull ossification defects Lampros A. Mavrogiannis, Ileana Antonopoulou, Alica Baxová, Stepán Kutílek, Chong A. Kim, Sofia M. Sugayama, ...

At CERN, the European Organization for Nuclear Research, physicists and engineers are probing the fundamental structure of the universe. They use the world's largest and most complex scientific ...