EBC-129 is a first-in-class antibody drug conjugate (ADC) targeting a novel, tumor-specific N256-glycosylated epitope on CEACAM5 and CEACAM6. The updated findings showed promising efficacy data ...

Navigator is also advancing NAV-242, a next-generation, engineered anti-OX40L/TNFα antibody, with half-life-extension, which has the potential for optimized exposure and dosing profile to provide a ...

Researchers have found evidence of a previously unrecognized soft tissue structure in the cheek region of many dinosaur species, which they've called the "exoparia." The finding deepens our ...

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Mapping an antibody’s epitope, where it binds a target, can now be done in three dimensions, which optimizes the selection of application-specific antibodies April 3, 2025 ...

If the antibody interacts with a key part of a microbial structure, it can block infection. Antibodies (like their targets) come in a dizzying array — which means that some antibodies block their ...

The company aims to supercharge antibody treatments using specially designed protein “cages” that multiply their effects, opening up new opportunities in drug development.

Antibody-drug conjugates (ADCs) are fusions of therapeutic drugs and antibodies conjugated by a linker, designed to deliver a therapeutic payload to cells expressing the target antigen. By delivering ...

Correspondence Antibody Fingerprints Linking Adenoviral Anti-PF4 Disorders Published May 15, 2024 N Engl J Med 2024;390: 1827 - 1829 DOI: 10.1056/NEJMc2402592 ...

In a paper recently published on hLife, Chinese scientists elucidate the 3.04 Å cryo-EM structure of HSV-1 gB bound to the neutralizing antibody D48. Through structural and sequence comparison ...

More information: Mengfan Lyu et al, The structure of the teleost Immunoglobulin M core provides insights on polymeric antibody evolution, assembly, and function, Nature Communications (2023).

The structure of the teleost Immunoglobulin M core provides insights on polymeric antibody evolution, assembly, and function. Nature Communications, 2023; 14 (1) DOI: 10.1038/s41467-023-43240-z ...