This useful study reports a method to detect and analyze a novel post-translational modification, lysine acetoacetylation (Kacac), finding it regulates protein metabolism pathways. The study unveils ...

Partnered Assets: SIRPα antagonists BI 765063 and BI 770371, an improved next generation SIRPα inhibitor, developed in partnership with Boehringer Ingelheim: Rapid Oral Abstracts of the Phase 1 ...

Partnered Assets: SIRPα antagonists BI 765063 and BI 770371, an improved next generation SIRPα inhibitor, developed in partnership with Boehringer Ingelheim: Rapid Oral Abstracts of the Phase 1 ...

Aftab, Lisa D. Belmont, Jae H. Chang. XL495 is a potent, selective, and orally bioavailable inhibitor of PKMYT1 [abstract]. In: Proceedings of the American Association for Cancer Research Annual ...

Metastatic, castration-resistant prostate cancer (mCRPC) directly contributes to the mortality and morbidity of prostate cancer. It is imperative to identify new molecular targets and discover ...

How alterations in cell metabolism translate into specific developmental gene programs remains a major question. This study ...