By using antibodies from a human donor with a self-induced hyper-immunity to snake venom, scientists have developed the most ...

Peripheral nerve injury triggers synaptic remodeling. The ganglioside GT1b stabilizes spinal excitatory synapses by ...

Introduction: Cardiac fibrosis is one of the major pathophysiologic features of ischemic cardiac disorders and substantial evidence has shown that cardiac fibroblasts and their activated form ...

Viability was assessed by performing XTT-assay to determine the effect of BRD9 inhibition in TGCT cell lines. FACS analysis was used to display changes in cell cycle distribution as well as apoptosis.

Our findings revealed that the effects of IR on cell adhesion and mechanics are contingent upon both the dose administered and the stiffness of the substrate on which the cells are cultured.

Alternate splicing of PRKG1 transcripts confers distinct leucine zippers, linkers, and auto-inhibitory (AI) pseudo-substrate sequences to PKG Iα and Iβ that result in isoform-specific activation ...

Cytokine secretion is captured by the anti-cytokine antibodies in the next 24–48 h with detection antibody and enzyme substrate being added just ... due to issues surrounding potential drug-inhibition ...

Here, we test the therapeutic potential of selectively inhibiting MMP14 using an affinity matured exosite inhibitor termed E2C6 with the primary aim of preventing endothelial Tie2 shedding in vitro in ...