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Novel AI method sheds light on how enzyme linked to Alzheimer's selects its targets
Researchers from DZNE, Ludwig-Maximilians-Universität München (LMU), and Technical University of Munich (TUM) have found that ...
Study analyzes 400 million years of enzyme evolution
Enzymes catalyze chemical reactions in organisms—without which life would not be possible. Leveraging AlphaFold2 artificial ...
Science Daily1d
MIT scientists just supercharged the enzyme that powers all plant life
Scientists at MIT have turbocharged one of nature’s most sluggish but essential enzymes—rubisco—by applying a cutting-edge ...
Key mechanisms of enzyme involved in rare metabolic disease identified
An international research team has published a study in the journal The FEBS Journal that significantly advances the ...
Selective biocatalyst targets styrene pollutant, yielding pure epoxides for pharmaceuticals and specialty chemicals
Doctoral students have described a new selective biocatalyst in an interdisciplinary and inter-university collaboration. The ...
C&EN4d
Inverting the Enantioselectivity of a Carbonyl Reductase via Substrate−Enzyme Docking-Guided Point Mutation | Organic Letters - ACS Publications
Substrate-enzyme docking-guided point mutation of a carbonyl reductase from Sporobolomyces salmonicolor led to mutant enzymes, which reversed the enantiopreference and enhanced the enantioselectivity ...