We are at an inflection point that is driving a renaissance in antibody-drug conjugate (ADC) development. As successes in the clinic have led to more U.S. Food & Drug Administration (FDA) approvals, ...

Results from a Phase Ia/Ib trial show that Eli Lilly’s LY4170156, an antibody drug conjugate (ADC) targeting folate receptor alpha (FRα), demonstrated notable anti-tumor activity in women with heavily ...

Conjugated polymers are organic macromolecules that are characterized by a backbone chain of alternating double- and single-bonds. Their overlapping p-orbitals create a system of delocalised π ...

This paper aims to identify the current state of the art of the latest research related to Conjugate Gradient (CG) methods for unconstrained optimization through a systematic literature review ...

Complex-valued neural networks (CVNNs) have become a hot research topic in neural network community for their powerful ability in dealing with complex-valued signal problems. However, as one of the ...

This review is organized into six sections: (1) the progression from traditional modeling approaches to AI-driven design of individual ADC components; (2) the application of deep learning (DL) to ...

(UroToday.com) The 2025 ASCO annual meeting featured a urothelial carcinoma rapid oral abstract session and a presentation by Dr. Xinan Sheng discussing results from a phase 1b/2 study assessing ...

A dynamic molecular system undergoing sequential reconfiguration and multi-state fluorescence switching via intramolecular oxa/thiol-Michael conjugate addition–elimination reactions is reported.