Progressive Proximal-to-Distal Reduction in Expression of the Tight Junction Complex in Colonic Epithelium of Virally-Suppressed HIV Individuals. PLoS Pathogens , 2014; 10 (6): e1004198 DOI: 10. ...

The tight junction complex forms tiny strands to seal that intercellular space. Levine and colleagues demonstrated in their investigation that patients whose HIV was well controlled with ...

Claudins are tetraspan transmembrane tight-junction proteins that regulate epithelial barriers. In the distal airspaces of the lung, alveolar epithelial tight junctions are crucial to regulate ...

The tight junction is a multiprotein complex consisting of numerous proteins that include ZO-1, claudin-1 and occludin. A total of 35 cases of synovial sarcoma (13 biphasic, ...

In addition, the 200-kDa complex formation in polarized Caco-2 cells results in the removal of occludin from tight junctions and increased paracellular permeability.

Tight junctions are multi-protein complexes that serve as barriers in epithelial tissues such as the skin or lining of the gut. Loss of a specific tight junction barrier protein, ...

Tight junctions are multi-protein complexes that serve as barriers in epithelial tissues such as the skin or lining of the gut. Loss of a specific tight junction barrier protein, claudin 18 ...

Tight junctions are multi-protein complexes that serve as barriers in epithelial tissues such as the skin or lining of the gut. Loss of a specific tight junction barrier protein, claudin 18 ...

A team led by researchers at St. Jude Children's Research Hospital report that mice lacking the protein Alix develop hydrocephalus or "water on the brain." Alix ensures that epithelial cells of ...

Our bodies and organs are shielded from the external environment by tissue barriers like the skin. These barriers must be ...

Tight junctions must be able to adapt to cell shape change and still be able to seal the gaps," explains Prof. Honigmann, chair of Biophysics and research group leader at the BIOTEC.