We are at an inflection point that is driving a renaissance in antibody-drug conjugate (ADC) development. As successes in the clinic have led to more U.S. Food & Drug Administration (FDA) approvals, ...

The partnership was designed to create a turnkey offering for biopharmaceutical companies seeking antibody drug conjugate (ADC) and bioconjugation, linker/payload manufacturing, drug product ...

Results from a Phase Ia/Ib trial show that Eli Lilly’s LY4170156, an antibody drug conjugate (ADC) targeting folate receptor alpha (FRα), demonstrated notable anti-tumor activity in women with heavily ...

Conjugated polymers are organic macromolecules that are characterized by a backbone chain of alternating double- and single-bonds. Their overlapping p-orbitals create a system of delocalised π ...

Transferrin receptor 1 (TfR1) is a ubiquitously expressed receptor characterized by rapid internalization kinetics and efficient receptor recycling, making it an attractive target for drug delivery.

Read the history behind Andrés González’s hymn “Placentero nos es trabajar” — now included in the new hymnbook as “Oh, How Great Is Our Joy” — and what it’s taught Spanish-speaking Latter-day Saints ...

This paper aims to identify the current state of the art of the latest research related to Conjugate Gradient (CG) methods for unconstrained optimization through a systematic literature review ...

Complex-valued neural networks (CVNNs) have become a hot research topic in neural network community for their powerful ability in dealing with complex-valued signal problems. However, as one of the ...

This review is organized into six sections: (1) the progression from traditional modeling approaches to AI-driven design of individual ADC components; (2) the application of deep learning (DL) to ...