Mechanistic discrepancies between species highlights the limitations of mouse models in advancing STING inhibition drugs for various diseases.

Tau protein is essential for microtubule stability and neuronal function. The protein’s disfunction is linked to several ...

Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

Insects possess a remarkable ability to develop innate immune memory, and the mechanisms underlying this process are becoming a central topic in innate immunity research.