Targeted cancer drugs known as CDK4/6 inhibitors have improved outcomes for patients with advanced or metastatic HR+/HER2- ...

Patients with ID receiving TNF inhibitors are at greater risk for cutaneous malignancy than patients who are biologic-naïve.

Inflammatory mediators like cytokines and chemokines play a key role in driving age-related and postmenopausal breast cancer progression and immune system changes.

Age-related and postmenopausal breast cancer progression remains a significant challenge, with growing evidence pointing to the role of pro-inflammatory cytokines and CXC chemokines in tumor ...

Role of transcription factor SOX30 in triple-negative breast cancer metastasis and tumor immune microenvironment through the TNF/TNFR2-NF-κB-CCL20/CCR6 axis. Authors: Pingping Gao, Ning Yang, Na Sun, ...

According to a new report, the global Tumor Microenvironment Market will grow from US$ 1.47 Billion in 2023 to US$ 3.43 billion by 2030 at a compounded annual growth rate (CAGR) of 12.9% during the ...

Secreted factors from M1 macrophages drive prostate cancer stem cell plasticity by upregulating NANOG, SOX2 , and CD44 through NFκB-signaling. OncoImmunology, 2024; 13 (1) DOI: 10.1080/2162402X ...

Tumor necrosis factor (TNF) is a type of cytokine. This is a signaling protein made by your white blood cells. Cytokines are released during an immune system response to threats such as tumor cells, ...

Then, we systematically correlated the TNF risk score with the tumor microenvironment (TME) cell infiltration, molecular subtypes of BLCA, and the potential value for predicting the efficacy of ...

ADC-intrinsic Ikkα ablation up-regulated expression of regulators of macrophage recruitment and Treg differentiation, thereby converting the tumor microenvironment (TME) from cancer restrictive to ...

Keywords: TNF, head and neck cancer, tumor immune microenvironment, immunotherapy, bioinformatics and biomarkers Citation: Long Q, Huang C, Meng Q, Peng J, Yao F, Du D, Wang X, Zhu W, Shi D, Xu X, Qi ...