In diseases due to exposure to toxic particles like gout, macrophages elicit separate pathways for inflammation and lysosomal ...

Human exposure to toxic particles drives various diseases. Examples include gout, an acute arthritis driven by monosodium ...

By creating artificial aging in mice, researchers at Lund University in Sweden have been able to track the formation of ...

When the macrophages’ ability to consume dying cancer cells or Upd3 production was decreased, tumor growth was significantly ...

Targeted Oncology connects oncology professionals with updates on immunotherapy, biomarkers, cancer pathways, and targeted ...

This is a useful study in the role of CHI3L1 in Kupffer cells, the macrophages of the liver, showing that CHI3L1 alters glucose regulation in obesity. Specifically, Chi3l1 protects glucose-dependent ...

On the other hand, peptide mimics represent a safe and viable therapeutic goal for blocking aberrant signaling pathways. The VEGF peptide mimic strategy involves direct binding to the VEGFR-2 ...

Skip to: Collagen Synthesis Factors Leading to Collagen Degradation Studies on Collagen Degradation Pathways Collagen is a major protein which is found in connective tissues and the extracellular ...