As a result, the curve for left ventricular diastolic pressure in relation to volume is shifted upward and to the left , chamber compliance is reduced, the time course of filling is altered, and ...

This pressure–volume curve, which describes left ventricular compliance, is normally curvilinear. Furthermore, alterations in left ventricular compliance shift the pressure–volume curve.

Figure 1 shows a simultaneous recording of pulmonary-artery wedge (pulmonary-capillary) and left-ventricle pressure pulses. The area between the two curves in diastole is the mitral-valve gradient.

Association Between Intensive vs Standard Blood Pressure Control and Incident Left Ventricular Conduction Disease: A Post Hoc Analysis of the SPRINT Randomized Clinical Trial. JAMA Cardiology ...