Cellular communication is a critical process that relies on exocytosis, during which cells release stored chemical messengers contained within intracellular nanoscale vesicles (50–500 nm in diameter).

Understanding the cellular uptake and exocytosis processes of nanoparticles (NPs) is essential for developing the nanomedicines and assessing the health risk of nanomaterials. Considerable efforts ...

Endocytosis vs exocytosis Endocytosis involves cells taking in substances from outside the cell by engulfing them in a vesicle derived from the cell membrane. Exocytosis is where cells shift materials ...

We observed exocytosis of CCL21ΔC-mCherry+ vesicles at the entire length of LEC junctions (Fig. 2B,C). However, exocytosis events were most abundant at 0–5 μm distance from the multicellular junction ...

Endothelial activation promotes the release of procoagulant extracellular vesicles and inflammatory mediators from specialized storage granules. Endothelial membrane exocytosis is controlled by ...

The release of peptide hormones or neurotransmitters from neuroendocrine cells is essential for the co-ordination of diverse physiological events. Secretory vesicles derived from the trans-Golgi ...

Rac1 activation restores exocytosis of these granules. “ In vivo, WASH deficiency induces exacerbated azurophilic granule exocytosis, inflammation, and decreased survival.

Lysosomal exocytosis releases pathogenic α-synuclein species from neurons in synucleinopathy models. Nature Communications, 2022; 13 (1) DOI: 10.1038/s41467-022-32625-1 ...

Here's a look at whether Earth is getting closer to or farther from the sun, why that's happening and what effects it might have on our planet.

Using this method to study mitotic cells, the authors show that some cells lose dry mass early in mitosis by a mechanism involving exocytosis. This work improves upon the authors' method to measure ...

Nucleic acids are essential for all forms of life, and it is found in all cells. Nucleic acids come in two natural forms called deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). Image Credit ...