Next, Hydroxymethylglutaryl-CoA synthase can form the molecule HMG-CoA from another acetyl-CoA and the previously made acetoacetyl-CoA. The two proteins that facilitate this key enzyme activity ...

Organisms across all kingdoms of life crucially rely on a molecule called acetyl-CoA that fuels essential biochemical processes in cells, such as the production of fatty acids and cholesterol ...

The resulting acetyl-CoA molecules can be used to produce a desired chemical with higher carbon efficiency. The researchers dubbed their new hybrid pathway non-oxidative glycolysis, or NOG. "This ...

Immune cells use two different routes to produce acetyl-CoA, an essential metabolite required to fight infection and cancer, reports a study led by Van Andel Institute scientists.. The findings, ...

Noticing that many bacteria didn’t have one of the key enzymes used in the glyoxylate cycle, they worked out another way the bugs might convert acetyl-CoA to malate (Proceedings of the National ...

UCLA chemical engineering researchers have created a new synthetic metabolic pathway for breaking down glucose that could lead to a 50 percent increase in the production of biofuels.

More information: Chao Wu et al, Acetyl-CoA synthesis through a bicyclic carbon-fixing pathway in gas-fermenting bacteria, Nature Synthesis (2022). DOI: 10.1038/s44160-022-00095-4 Journal ...