Who Should I Start? Who Should I Sit? Some of the most common Week 17 fantasy football lineup decisions are regarding players ...

As Brock Purdy celebrated his 25th birthday Friday, the 49ers struggled to field and coach up healthy offensive lineman ahead ...

San Francisco 49ers rookie running back Isaac Guerendo (foot, hamstring) was limited in practice for the second straight day ...

San Francisco 49ers QB Brock Purdy discussed supporting the new offensive line and the team's mindset heading into their ...

As Brock Purdy celebrated his 25th birthday Friday, the 49ers struggled to field and coach up healthy offensive lineman ahead ...

Guerendo (foot/hamstring) practiced in a limited capacity Friday, Nick Wagoner of ESPN.com reports. Guerendo now has managed back-to-back capped sessions to kick off Week 17 prep as he looks to put ...

A year ago, the 49ers beat the Lions in the NFC Championship at Levi's Stadium. What a difference a year makes. On Thursday, ...

The San Francisco 49ers awaited promising news about the return of a key rookie to assist Brock Purdy amid Christian ...

The 49ers have been without Isaac Guerendo for most of December. But the RB helped provide a promising update Thursday.

The San Francisco 49ers’ practice schedule began a day later than normal with a Monday night showdown against the Detroit ...

When will Isaac Guerendo return and play? Will Isaac Guerendo be back again this season? Read the latest Isaac Guerendo ...

Veteran center Matt Hennessy just signed a two-year deal with the 49ers. To make room for Hennessy on the 53-man roster, they ...