During photosynthesis, an enzyme called rubisco catalyzes a key reaction—the incorporation of carbon dioxide into organic ...

DelveInsight’s Metastatic Prostate Cancer Pipeline report depicts a robust space with 80+ active players working to develop ...

More information: Kyle S. Gregory et al, Ciprofloxacin Inhibits Angiotensin I-Converting Enzyme (ACE) Activity by Binding at the Exosite, Distal to the Catalytic Pocket, ACS Bio & Med Chem Au (2025).

Geneva, Switzerland, May 12, 2025 - Addex Therapeutics (SIX/NASDAQ: ADXN), a clinical-stage biopharmaceutical company focused on developing a portfolio of novel small molecule allosteric modulators ...

NEW YORK, March 06, 2025--Allosteric Bioscience, Inc. (ABI), has announced today that it has licensed technology from Johns Hopkins University for the treatment or prevention of sarcopenia which ...

WALTHAM, Mass.--(BUSINESS WIRE)--Ensem Therapeutics, Inc. (ENSEM), a pioneering drug discovery and development company that leverages its unique Kinetic Ensemble® platform to advance innovative ...

Effect on Enzyme Kinetics Km: the affinity of the enzyme for the substrate (measured by K m) remains unchanged because the inhibitors bind to the allosteric site while the substrates bind to the ...

Reviewer #1 (Public Review): Summary: The authors identified nanobodies that were specific for the trypanosomal enzyme pyruvate kinase in previous work seeking diagnostic tools. They have shown that a ...

The kinetics of this reaction was previously studied using Henry-Michaelis-Menten and allosteric enzyme kinetics models, 22 but these models cannot adequately describe complex enzymatic reactions that ...