Organ-on-a-chip systems offer a more accurate, ethical, and scalable alternative to animal testing in drug discovery and ...

Many people, including researchers, recognize that animal models of human disease don't work as well as their colleagues and others claim that they do. I recently learned of an outstanding book by ...

Organoids, miniaturized, stem cell-derived versions of human organs, are revolutionizing biomedical research by offering human-specific models for disease study and drug testing. While they have ...

Animal models play a starring role in medical discoveries because they help scientists understand how living ... providing insights that could revolutionize treatments for human heart disease.

The lack of animal models that mimic human disease impedes the study of many pathologies that still lack treatment beyond symptom relief. This is what has happened so far with PURA syndrome, a rare ...

Animal models are often flawed and offer incomplete representations of human disease. Yet we have long relied on their data to establish the risk/benefit for experimental drugs.

Scientists sometimes compare predicting the course of epidemics to forecasting the weather. But there's a major ...

Frederick R. Appelbaum, MD, recognized for advancing marrow transplantation, talks about the impact of canine research on ...

They now are studying the VMA21 mutation in a mammalian model, the mouse, to further push research toward a possible clinical treatment. “We have established the first preclinical animal model of XMEA, ...