Sugar: In DNA, the sugar is deoxyribose, while in RNA, it is ribose.The sugar forms the backbone of the nucleic acid strand. Phosphate Group: The phosphate group is attached to the sugar and helps ...

Natural nucleic acids like DNA and RNA have a sugar-phosphate "backbone" and nitrogen-based components; while the nitrogen-based components in SNA and L-aTNA remain the same, they have an amino ...

Artificial nucleic acids with a fixed conformation of the backbone of the oligonucleotide can form stable duplexes, however, the synthesis of modified nucleotides with non-canonical three ...

Peptide nucleic acids (PNAs) are artificial polymers that were originally invented in 1991 to be synthetic mimics of DNA. Instead of having a deoxyribose phosphate backbone like DNA, PNA has a ...

Nucleic acids are essential for the functioning and development of living organisms. DNA carries genetic information that determines traits such as eye color and susceptibility to diseases in ...

A biochemical breakthrough using simple carbon atoms, by Ken Yamada, Ph.D., and Anastasia Khvorova, Ph.D., has dramatically improved the stability and efficacy of a potential oligonucleotide ...

Summary Peptide Nucleic Acid (PNA) is a synthetic polymer similar to DNA or RNA. PNA can be said to have been born in Denmark, where it was originally developed by Peter E. Nielsen (University of ...